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Title: The total synthesis of fukiic acid, an HIV-1 integrase inhibitor
Authors: Queffélec, Clémence
Bailly, Fabrice
Mbemba, Gladys
Mouscadet, Jean-François
Debyser, Zeger
Witvrouw, Myriam
Cotelle, Philippe # ×
Issue Date: Oct-2008
Series Title: European Journal of Medicinal Chemistry vol:43 issue:10 pages:2268-2271
Abstract: A successful synthesis of fukiic acid is described in 7% overall yield (6 steps from veratraldehyde). rac-Fukiic acid was found to be a potent inhibitor of HIV-1 integrase but did not reveal any antiviral activity in the MT-4 cells assay.
ISSN: 0223-5234
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Virology and Gene Therapy
× corresponding author
# (joint) last author

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