Title: An antiviral factor from Melia azedarach L. prevents Tacaribe virus encephalitis in mice
Authors: Andrei, Graciela ×
Lampuri, J S
Coto, C E
de Torres, R A #
Issue Date: Jul-1986
Series Title: Experientia vol:42 issue:7 pages:843-5
Abstract: Treatment of neonatal mice with an antiviral factor, (AVF), obtained from the leaves of Melia azedarach L. protected them against lethal encephalitis caused by Tacaribe virus inoculation. The degree of protection obtained varied from 66% to 100% depending on the virus dose. Similarly, administration of AVF to nursing mothers protected their offspring from developing virus encephalitis. AVF does not directly inactivate Tacaribe virus; it inhibits an early step (s) in the replication process in cell cultures.
ISSN: 0014-4754
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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