Title: A simple nucleic acid alternative: aminopropyl nucleic acids (APNAs)
Authors: Zhou, Ding
Schepers, Guy
Van Aerschot, Arthur # ×
Issue Date: 2007
Publisher: Taylor & francis inc
Series Title: Nucleosides nucleotides & nucleic acids vol:26 issue:10-12 pages:1665-1668
Abstract: Aminopropyl nucleic acids are constitutionally simple nucleic acids alternatives with one chiral center per nucleotide and with the constitutional potential to hybridize with RNA. Both R and S isomers of the 3'- or 2'-aminopropyl nucleosides were incorporated either into DNA or likewise were used for fully modified sequences. The (R)-adenine analogue, yielding (S)-APNA, can be considered as a candidate for universal base pairing.
ISSN: 1525-7770
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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