Title: Effect of peripheral obestatin on food intake and gastric emptying in ghrelin-knockout mice
Authors: Depoortere, Inge ×
Thijs, Theo
Moechars, D
De Smet, Betty
Ver Donck, L.
Peeters, Theo #
Issue Date: Apr-2008
Publisher: Nature publishing group
Series Title: British Journal of Pharmacology vol:153 issue:7 pages:1550-1557
Abstract: Background and purpose: The finding that obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's stimulatory effect on food intake and gastric emptying has been questioned. The effect of obestatin has been mostly investigated in fasted rodents, a condition associated with high blood levels of ghrelin which may mask the effect of obestatin. We therefore investigated the effect of obestatin on food intake, gastric emptying and gastric contractility in ghrelin knockout mice.
ISSN: 0007-1188
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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