Title: Cross-metathesis mediated synthesis of new acyclic nucleoside phosphonates
Authors: Roy, Vincent ×
Kumamoto, Hiroki
Berteina-Raboin, Sabine
Nolan, Steven R
Topalis, Dimitrios
Deville-Bonne, Dominique
Balzarini, Jan
Neyts, Johan
Andrei, Graciela
Snoeck, Robert
Agrofoglio, Luigi A #
Issue Date: 2007
Publisher: Marcel Dekker
Series Title: Nucleosides, Nucleotides & Nucleic Acids vol:26 pages:1399-402
Conference: XVII International Round Table on Nucleosides, Nucleotides and Nucleic Acids location:Bern, Switzerland date:3-7 September 2006
Abstract: With the commercial availability of well-defined ruthenium metathesis catalysts which combine high stability and broad junctional group compatibility, olefin metathesis is now routinely integrated in various syntheses. We will report here the overwhelming power and scope of cross-metathesis in the area of new acyclic nucleoside phosphonates. Scope and limitations of this approach, and especially the E/Z stereocontrol, are discussed on selected examples from our drug discovery group.
ISSN: 1525-7770
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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