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Title: Second primary lung cancer in Flanders: frequency, clinical presentation, treatment and prognosis
Authors: Van Meerbeeck, J ×
Weyler, J
Thibaut, A
Vansteenkiste, Johan
Aumann, J
Deneffe, Georges
Galdermans, D
Haelterman, M
Joos, Gustaaf
Noppen, M
Pinson, P
Tasson, J
van den Eeckhout, A
Uydebrouck, M #
Issue Date: Mar-1997
Series Title: Lung cancer (Amsterdam, Netherlands) vol:15 issue:3 pages:281-95
Abstract: Patient and tumour characteristics of 23 patients presenting with a second primary lung cancer were analysed and compared with 534 patients with radically resected stage 1 non-small cell lung cancer (NSCLC). None of these characteristics is associated with a higher occurrence rate for second primary lung cancer. Prognosis in the latter patients is significantly worse than after resection of a 'solitary' NSCLC: the median survival time (MST) after resection of the first tumour is 50 months; after diagnosis of the second tumour only 14 months. Surgically retreated patients have a prognosis that is similar to that after resection of a 'solitary' NSCLC. No separate independent prognostic factors responsible for this survival difference could be isolated. Squamous histology and central location are associated with a longer recurrence free survival time. We conclude that the occurrence of a second primary lung cancer can not be predicted based on patient or tumour characteristics and that only surgical retreatment offers a chance of long survival in these patients.
ISSN: 0169-5002
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Anatomy Section (-)
× corresponding author
# (joint) last author

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