Title: Prevalence and correlates of self-reported pretransplant nonadherence with medication in heart, liver, and lung transplant candidates
Authors: Dobbels, Fabienne ×
Vanhaecke, Johan
Desmyttere, Ariane
Dupont, Lieven
Nevens, Frederik
De Geest, Sabina #
Issue Date: Jun-2005
Publisher: Lippincott Williams & Wilkins
Series Title: Transplantation vol:79 issue:11 pages:1588-1595
Abstract: BACKGROUND: Evidence on prevalence and correlates of pretransplant medication nonadherence (MNA) is limited. The present study explored self-reported prevalence and correlates of MNA before heart, liver, and lung transplantation. METHODS: This cross-sectional descriptive study included 174 patients: 69 lung, 33 heart, and 72 liver transplant candidates. MNA was assessed by self-report using the following question: "During the past 14 days, how often did you not take your medication?" Patients scoring once or higher on a five-point rating scale were considered to be nonadherent. Correlates of MNA explored were demographics, anxiety and depression (Hospital Anxiety and Depression Inventory), personality traits (NEO Personality Inventory-Revised), perceived health status (Euro-QOL), and social support (Social Support Questionnaire). RESULTS: Prevalence of pretransplant MNA was 16.7% and was comparable among the three groups. After correction for multiple comparisons (i.e., P=0.01), higher educational level (P=0.006) was related to MNA. Less severe depression (P=0.069), lower scores on the personality trait conscientiousness (P=0.021), and less received social support (P=0.062) tended to be related to MNA. Multiple logistic regression revealed that higher educational level (P=0.008), lower received social support (P=0.013), and lower conscientiousness (P=0.023) were independent predictors of pretransplant MNA. CONCLUSIONS: Several correlates of MNA allow identification of patients at risk for pretransplant MNA.
ISSN: 0041-1337
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Academic Centre for Nursing and Midwifery
Interfaculty Centre for Biomedial Ethics and Law
× corresponding author
# (joint) last author

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