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Title: Clinical significance of squamous cell carcinoma antigen in cancer of the human uterine cervix. Comparison with CEA and CA-125
Authors: Verlooy, H ×
Devos, P
Janssens, J
Mortelmans, Luc
Gerits, M
Bonte, Jan
De Roo, Michel #
Issue Date: Feb-1991
Series Title: Gynecologic and obstetric investigation vol:32 issue:1 pages:55-8
Abstract: Serum squamous cell carcinoma antigen (SCCa) concentrations were determined by a radioimmunoassay kit before and during the treatment of 50 patients with cervical carcinoma: 44 with squamous cell carcinoma (SCC) and 6 with adenocarcinoma. The positivity rate of SCCa was 50% (52% for SCC and 33% for adenocarcinoma). The sensitivity of SCCa for SCC was twice as high as that of CEA and CA-125. Low serum concentrations were observed in early-stage carcinoma, indicating that SCCa is not useful for diagnosis. In advanced cases, serum levels were directly and significantly correlated with the stage of the disease.
ISSN: 0378-7346
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
Nuclear Medicine & Molecular Imaging
× corresponding author
# (joint) last author

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