Author:

Keywords:

Adult, Anti-Ulcer Agents, Double-Blind Method, Esophagus, Humans, Male, Peristalsis, Prostaglandins E, Prostaglandins, Synthetic, Rioprostil, 1103 Clinical Sciences, Gastroenterology & Hepatology, 3202 Clinical sciences

Abstract:

The aim of this investigation was to study, in healthy human volunteers, the effect of two different doses of rioprostil, a PGEj analogue, on lower oesophageal sphincter (LES) pressure and deglutitive motor activity of the oesophageal body and LES. The double-blind, placebo-controlled study was performed in 10 healthy male volunteers, aged 19-28 years. © 1989 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.