Title: Modulating the endocrine response in sepsis: insulin and blood glucose control
Authors: Vanhorebeek, Ilse ×
Langouche, Lies
Van den Berghe, Greet #
Issue Date: 22-Mar-2007
Series Title: Novartis Foundation symposium vol:280 pages:204-15; discussion 215-22
Abstract: Hyperglycaemia is a common feature of the critically ill and has been associated with increased mortality. Maintaining normoglycaemia with insulin therapy improves survival and reduces morbidity in prolonged critically ill patients in both surgical and medical intensive care units, as shown by two large randomized controlled studies. Prevention of cellular glucose toxicity by strict glycaemic control appears to play a predominant role, but also other metabolic and non-metabolic effects of insulin appear to contribute to the clinical benefits.
ISSN: 1528-2511
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Intensive Care Medicine
× corresponding author
# (joint) last author

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