Title: Combined manometric and radiological study of the changes in colonic motility induced by sennosides in rats
Authors: Spiessens, C ×
Ceuterick, L
Ponette, Eric
Janssens, Jozef
Lemli, Jozef #
Issue Date: Jun-1988
Series Title: Pharmacology vol:36 Suppl 1 pages:66-72
Abstract: Colonic motility changes induced by sennosides in rats were studied by an original method, which permits the simultaneous projection of manometric and fluoroscopic registrations on a single monitor. The results of this study allowed us to confirm the laxative effect of sennosides by inducing mass movements within 60-80 min after intracecal administration leading to a complete emptying of the whole colon. These mass movements were preceded by hypotonia of cecum and colon and impeded pellet formation.
ISSN: 0031-7012
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiology
Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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