Title: Purification and amino acid sequence of human motilin isolated from a motilin containing liver metastasis
Authors: De Clercq, P ×
Vandermeers, A
Van Assche, Gert
Fiasse, R
Depoortere, Inge
Vandermeers-Piret, M C
Deprez, P
Peeters, Theo #
Issue Date: May-1995
Series Title: Regulatory peptides vol:55 issue:1 pages:79-84
Abstract: The acid extract of a liver metastasis from a patient with elevated plasma motilin levels contained large quantities of motilin (3.37 micrograms/ml). The extract was concentrated on a C18-column and motilin was isolated by gel chromatography (Sephadex G-50) followed by cation ion exchange chromatography (HR5/5 Mono-S) and three successive steps of reverse phase chromatography (Nucleosil 300-5 C18). The pure peptide was sequenced and the identity of porcine and human motilin was confirmed. This is the first report of a tumor containing large amounts of motilin.
ISSN: 0167-0115
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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