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Title: Morphological identification of alpha-I-antitrypsin in the human small intestine
Authors: Geboes, Karel ×
Ray, M B
Rutgeerts, Paul
Callea, F
Desmet, V J
Vantrappen, Gaston #
Issue Date: Apr-1982
Series Title: Histopathology vol:6 issue:1 pages:55-60
Abstract: Alpha-I-antitrypsin immunoreactivity was demonstrated by immunofluorescence in epithelial cells of the normal human small intestine. Its presence was also confirmed in biopsies of patients with Crohn's disease. Specific fluorescence was observed in only four out of 14 adult patients with coeliac disease. These results implicate the human small intestinal epithelium as a possible source of alpha-I-antitrypsin. The absence of positive cells may have implications in the aetiology of coeliac disease.
ISSN: 0309-0167
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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