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Title: A pancreatic mucinous cystadenoma in a man with mesenchymal stroma, expressing oestrogen and progesterone receptors
Authors: Wouters, K
Ectors, Nadine
Van Steenbergen, Werner
Aerts, R
Driessen, A
Van Hoe, L
Geboes, Karel #
Issue Date: Feb-1998
Series Title: Virchows Archiv vol:432 issue:2 pages:187-9
Abstract: A 43-year-old man presented with abdominal discomfort caused by relapsing pancreatitis. Radiological examination revealed a multilocular cystic mass in the tail of the pancreas, which was resected. Gross examination showed a multilocular cystic lesion measuring 2.5 cm in diameter and containing clear fluid. Microscopically, a mucinous cystadenoma with mesenchymal stroma was diagnosed. The lesion showed two different components: a cyst lined by a columnar, mucin-secreting epithelium and a moderate cellular stroma composed of spindle cells. The stromal element appeared similar to primitive mesenchyme. Immunohistochemical staining confirmed this origin through vimentin expression and showed moderate to strong nuclear staining with oestrogen and progesterone receptor antibodies. Cystadenomas are rare tumours of the pancreas, but mesenchymal stroma is uncommon in such tumours; it is more frequently described in the liver and the bile ducts, and primarily in women.
ISSN: 0945-6317
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Cell & Tissue Research
# (joint) last author

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