Title: Evaluation of on-line viable biomass measurements during fermentations of Candida utilis
Authors: November, EJ ×
Van Impe, Jan #
Issue Date: 2000
Series Title: Bioprocess Engineering vol:23 issue:5 pages:473-477
Conference: date:Katholieke Univ Leuven, Dept Food & Microbial Technol, B-3001 Heverlee, Belgium
Abstract: In this article the suitability of the Biomass Monitor for on-line measurement of viable biomass is thoroughly evaluated during aerobic fermentations of Candida utilis. Successively a number of specifications of the measuring device are discussed for the studied biological system. The optimal measurement frequency for the given experimental conditions is determined. Furthermore, reliable calibrations of the capacitance readings versus well-known off-line analysis of dry weight and plate counts of the yeast have been established. In addition, the impact of varying fermentation conditions such as stirrer speed and air flow rate together with the influence of the oxygen concentration and conductance of the medium on the capacitance signal have been studied and quantified when a significant influence was observed. It is illustrated that knowledge of the viable biomass during fermentations is very useful in the estimation of the specific growth rate of the organism.
ISSN: 0178-515X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Bio- & Chemical Systems Technology, Reactor Engineering and Safety Section
× corresponding author
# (joint) last author

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