Title: Homologues of natural killer cell receptors NKG2-D and NKR-P1 expressed in cattle
Authors: Govaerts, MM ×
Goddeeris, Bruno #
Issue Date: 2001
Series Title: Veterinary immunology and immunopathology vol:80 issue:3-4 pages:339-344
Conference: date:Katholieke Univ Leuven, Fac Agr & Appl Biol Sci, Lab Physiol & Immunol Domest Anim, B-3001 Leuven, Belgium
Abstract: Partial transcripts of the homologues in cattle, of the genes encoding the NKR-P1 and NKG2-D natural killer cell lectin-like receptor families, were cloned by reverse transcriptase-PCR from bovine spleen, Three different cDNAs were partially sequenced for the NKG2-D homologue, and two for the NKR-P1 homologue. Identity to human nucleotide sequences was of 90 and 75%, respectively, and all structural residues of C-type lectin carbohydrate recognition domains were conserved. The identification of two of its members allows to hypothesise the existence of a bovine NK gene complex, prospectively located on chromosome 5. (C) 2001 Elsevier Science B.V. All rights reserved.
ISSN: 0165-2427
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
× corresponding author
# (joint) last author

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