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Title: Conservation of deduced amino acid sequence of FimH among Escherichia coli of bovine, porcine and avian disease origin
Authors: Vandemaele, FJ ×
Hensen, SM
Goddeeris, Bruno #
Issue Date: 2004
Publisher: ELSEVIER SCIENCE BV
Series Title: Veterinary microbiology vol:101 issue:2 pages:147-152
Conference: date:Katholieke Univ Leuven, Lab Physiol & Immunol Domest Anim, B-3001 Louvain, Belgium; State Univ Ghent, Fac Vet Med, Dept Virol Parasitol & Immunol, B-9820 Merelbeke, Belgium; Intervet Int BV, Bacteriol R&D, Boxmeer, Netherlands
Abstract: The FimH subunit of type I pili mediates adhesion of Escherichia coli to epithelium in different animal hosts. In this study, we sequenced and analyzed the fimH genes of 24 E. coli strains from bovine and porcine clinical cases. The obtained sequences were compared among each other and also with 24 known fimH sequences from avian E. coli strains. This comparison revealed a substantial homology (>99%) among strains from the different animal species origins. Moreover, specific mutations were found, some of which were present more frequently in avian strains or in bovine and porcine strains. (C) 2004 Elsevier B.V. All rights reserved.
ISSN: 0378-1135
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
× corresponding author
# (joint) last author

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