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Title: Cytogenetic investigation of synchronous bilateral renal tumors
Authors: Dal Cin, Paola ×
Van Poppel, Hendrik
Van Damme, Boudewijn
Baert, Luc
Van den Berghe, Herman #
Issue Date: Aug-1996
Series Title: Cancer genetics and cytogenetics vol:89 issue:1 pages:57-60
Abstract: Cytogenetic investigations on synchronous bilateral renal tumors are scarce. We report our findings on 13 renal tumors from 5 patients and review the literature. In bilateral as well as in solitary tumors, cytogenetic findings in each tumor correlated with the histological patterns, i.e. combinations of trisomies for papillary renal cell carcinoma, loss of 3p-material for non-papillary renal cell carcinoma, and coincident loss of the Y chromosome and chromosome 1 in oncocytomas. Bilateral multifocal renal cell carcinomas were always of the papillary type and the karyotypes showed more or less the same numerical anomalies, with trisomies in different combinations in tumors within the same kidney as well as in both kidneys. Structural changes, in contrast, were different from tumor to tumor.
ISSN: 0165-4608
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Urology Section (-)
Translational Cell & Tissue Research
Clinical Genetics Section (-)
× corresponding author
# (joint) last author

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