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Title: Surgical gastro-intestinal complications in 277 renal transplantations
Authors: LERUT, J ×
Lerut, Antoon
Gruwez, Jacques
Michielsen, Paul
VANRENTERGHEM, I
Van Renterghem, I #
Issue Date: 1980
Publisher: ASSOC SOC SCIENTIFIQUE MED BELGES
Series Title: Acta Chirurgica Belgica vol:79 issue:6 pages:383-389
Conference: date:ACAD HOSP ST RAFAEL,B-3000 LOUVAIN,BELGIUM
Abstract: In 277 consecutive renal transplantations, 49 of 254 patients (19%) developed a gastrointestinal complication causing a mortality rate of 29% (14/49 patients). Oesophageal, gastro-duodenal, pancreatic and ileocolonic complications are reviewed and discussed. Acute gastro-duodenal ulcerations proved to be the most common problem (45--22/49 patients). The loss of allograft in this group of 22 patients was 42% (9/22 patients). To overcome their high mortality (27%--6/22 patients) efforts were made to prevent these complications. After introduction of prophylactic surgery, mortality dropped from 4 to 2%, after systematic long-term prophylactic use of cimetidine, mortality even dropped to 0%. In this last series of 52 patients only one bleeding ulcer was seen immediately after allograft nephrectomy. Ileocolonic complications in renal transplant patients, difficult to diagnose and treat, are associated with a high morbidity and lethality. In 6 patients with colonic complications, 4 could be saved by early and aggressive surgery (67% survival rate). Two recipients developed a de novo gastrointestinal malignancy. Early, accurate, diagnosis and surgical therapy of gastro-intestinal complications after renal transplantation are directly related to the graft and/or patient survival rate. Every effort is therefore necessary to prevent these complications.
ISSN: 0001-5458
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Thoracic Surgery
Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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