Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease
Goris, An * × Williams-Gray, Caroline H * Clark, Graeme R Foltynie, Thomas Lewis, Simon J. G Brown, Joanne Ban, Maria Spillantini, Maria G Compston, Alastair Burn, David J Chinnery, Patrick F Barker, Roger A Sawcer, Stephen J #
Annals of neurology vol:62 issue:2 pages:145-153
Objective: Parkinson's disease (PD) is a neurodegenerative condition that typically presents as a movement disorder but is known to be associated with variable degrees of cognitive impairment including dementia. We investigated the genetic basis of susceptibility to and cognitive heterogeneity of this disease.