Title: Tc-99m HM-PAO labelled leucocyte scanning for detection of infection in orthopedic surgery
Authors: Verlooy, H ×
Mortelmans, Luc
Verbruggen, Alfons
Stuyck, Jos
Boogaerts, Marc
De Roo, Michel #
Issue Date: Mar-1991
Series Title: Progress in clinical and biological research vol:355 pages:181-7
Abstract: The use of labelled granulocyte scintigraphy is recognized as a reliable method for detecting osteomyelitis and other skeletal sepsis. Tc-99m hexamethyl propyleneamine oxime (Tc-99m HM-PAO), a lipophilic chelate offers the advantages of availability, lower radiation dose and higher image resolution, compared to other labelling agents. We have scanned 36 orthopedic patients with suspected infection, using autologous granulocytes labelled with Tc-99m HM-PAO. In all cases, scans were compared with clinical, microbiological and/or surgical findings. Sensitivity was 94% and specificity was 80%. We therefore believe that Tc-99m HM-PAO leucocyte scanning provides a useful method for detecting osteomyelitis and other skeletal infections.
ISSN: 0361-7742
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiopharmaceutical Research
Hematology Section (-)
Nuclear Medicine & Molecular Imaging
× corresponding author
# (joint) last author

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