Title: Intravenous ionic contrast media cause local prostacyclin release in man
Authors: De Maeyer, P ×
Deckmyn, Hans
Arnout, Jozef
Baert, A L
Vermylen, Jozef #
Issue Date: 1985
Publisher: Lippincott-raven publ
Series Title: Investigative radiology vol:20 issue:8 pages:871-873
Abstract: The effect of intravenous administration of ionic contrast media on local release of prostacyclin (PGI2) was investigated in man. Iodamide and ioxaglate, high- and low-osmolality contrast media, respectively, both significantly increased PGI2 levels at the site of injection. Iodamide was the most active, whereas an identical volume of isotonic saline had no effect. This study suggests that local formation of PGI2 may adequately reflect the degree of endothelial irritation that is caused by contrast media and that depends in part on their osmolality.
ISSN: 0020-9996
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular and Vascular Biology
Chemistry, Campus Kulak Kortrijk
Interdisciplinary Research Facility Life Sciences, Campus Kulak Kortrijk
Biomedical Sciences Group Management - miscellaneous
Faculty of Medicine - miscellaneous
× corresponding author
# (joint) last author

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