Title: Value of health-related quality of life to predict disability course in multiple sclerosis
Authors: Visschedijk, MAJ ×
Uitdehaag, BMJ
Klein, M
van der Ploeg, E
Collette, EH
Vleugels, Luc
Pfennings, LEMA
Hoogervorst, ELJ
van der Ploeg, HM
Polman, CH #
Issue Date: Dec-2004
Publisher: Lippincott williams & wilkins
Series Title: Neurology vol:63 issue:11 pages:2046-2050
Abstract: Objective: To determine the value of health-related quality of life (HRQoL) to predict change in disability status in patients with multiple sclerosis (MS). Methods: Over a 5-year period, data were collected on HRQoL ( Medical Outcomes Study Short Form-36 Health Survey) and disability status ( Expanded Disability Status Scale) from a heterogeneous group of 81 Dutch-speaking patients with MS. Results: Multivariate logistic regression analysis showed that HRQoL in the domains of Physical Functioning and Role - Physical Functioning is a significant predictor of change in disability status. Conclusions: A patient's subjectively perceived health-related quality of life may not be only a clinically and psychosocially meaningful outcome per se but may also be a predictor of objective outcomes such as change in disability status over a substantial period of time.
ISSN: 0028-3878
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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