Title: A post-tetanic time window for the reinforcement of long-term potentiation by appetitive and aversive stimuli
Authors: Seidenbecher, T ×
Reymann, KG
Balschun, Detlef #
Issue Date: Feb-1997
Publisher: Natl acad sciences
Series Title: Proceedings of the National Academy of Sciences of the United States of America vol:94 issue:4 pages:1494-1499
Abstract: Current theories on the encoding and storage of information in the brain commonly suppose that st short-term memory is converted into a lasting one; thus, it becomes consolidated over time, Within a finite period after a short-term memory can be reinforced by behavioral and humoral stimuli, We have found that, longterm potentiation (LTP), a likely candidate for a memory-encoding mechanism at the cellular level, displays similar features, LTP in the dentate gyrus of freely moving rats was reinforced after its induction by appetitive and aversive stimuli, The efficacy of these stimuli terminates about 1 h after tetanization, which mag reflect the time constants of the mechanisms underlying the consolidation that takes place. The reinforcement by appetitive and aversive stimulation was blocked by the beta-adreneraic antagonist propranolol, implicating norepinephrine in the underlying cellular processes.
ISSN: 0027-8424
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Biological Psychology
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science