Title: Differential acquisition, extinction, and reinstatement of conditioned suppression in mice
Authors: Dirikx, Trinette
Beckers, Tom
Muyls, Clara
Eelen, Paul
Vansteenwegen, Debora
Hermans, Dirk
D'Hooge, Rudi # ×
Issue Date: 2007
Publisher: Psychology Press
Series Title: The Quarterly Journal of Experimental Psychology vol:60 issue:10 pages:1313-1320
Abstract: In animals, the reappearance of conditioned fear responses after extinction has been primarily investigated using single-cue conditioning paradigms. However, a differential paradigm can overcome several of the disadvantages associated with a single-cue procedure. In the present study, the reinstatement phenomenon was assessed in mice using a differential conditioned suppression paradigm. In a first phase, one conditioned stimulus (CS+) was consistently paired with an unconditioned stimulus (US; footshock) while another CS (CS-)was not, resulting in selective suppression of previously trained instrumental behaviour during the CS+. After the extinction phase, half of the animals (reinstatement group) were presented with unsignalled USs, while the other half were not (control group). A differential return of conditioned responding was observed in the reinstatement group, but not in the control group. The implications of these findings for future conditioning research are discussed.
ISSN: 1747-0218
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Biological Psychology
Centre for Psychology of Learning and Experimental Psychopathology
× corresponding author
# (joint) last author

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