Title: Dermorphin sequence with high delta-affinity by fixing the phe side-chain to trans at alpha-1
Authors: Tourwe, D ×
Verschueren, Kristin
Vanbinst, G
Davis, P
Porreca, F
Hruby, Vj #
Issue Date: Oct-1992
Publisher: Pergamon-elsevier science ltd
Series Title: Bioorganic & medicinal chemistry letters vol:2 issue:10 pages:1305-1308
Abstract: The Phe sidechain in dermorphin was fixed into the trans conformation by linking the aromatic ring to the Gly nitrogen through a methylene bridge. The compound has high mu- and delta-opioid activities.
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Genetics Section (-)
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science