Title: Simple criterion for selection of flavonoid compounds with anti-HIV activity
Authors: Veljkovic, Veljko ×
Mouscadet, Jean-François
Veljkovic, Nevena
Glisic, Sanja
Debyser, Zeger #
Issue Date: Mar-2007
Publisher: Pergamon Press
Series Title: Bioorganic & Medicinal Chemistry Letters vol:17 issue:5 pages:1226-1232
Abstract: Flavonoid compounds represent an important natural source of antiretrovirals for AIDS therapy due to their significant anti-HIV-1 activity and low toxicity. Here we propose a simple theoretical criterion to discriminate active from inactive flavonoids that is suitable for rapid in silico screening of flavonoid libraries, and selection and optimization of lead compounds with anti-HIV-1 activity.
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Virology and Gene Therapy
× corresponding author
# (joint) last author

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