Title: Epithelial calcium channels: from identification to function and regulation
Authors: Hoenderop, Joost G J ×
Nilius, Bernd
Bindels, René J M #
Issue Date: Jun-2003
Series Title: Pflügers Archiv : European journal of physiology. vol:446 issue:3 pages:304-8
Abstract: The epithelial calcium channels TRPV5 and TRPV6 have been studied extensively in the epithelial tissues controlling Ca(2+) homeostasis and exhibit a range of distinctive properties that distinguish them from other transient receptor potential (TRP) channels. These two novel members of the superfamily of TRP channels were cloned from vitamin D-responsive epithelia: kidney, small intestine and placenta, and identified subsequently in tissues like pancreas, bone and prostate. This review addresses the unique properties of these highly Ca(2+)-selective channels and highlights their implications for the process of transepithelial Ca(2+) transport.
ISSN: 0031-6768
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Ion Channel Research
Department of Cellular and Molecular Medicine - miscellaneous
× corresponding author
# (joint) last author

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