Title: 5 alpha-dihydrotestosterone formation and its functional significance in rat anterior pituitary, subpopulations of gonadotrophs and cell cultures
Authors: Denef, Carl # ×
Issue Date: Oct-1983
Series Title: Journal of steroid biochemistry. vol:19 issue:1A pages:235-9
Abstract: The present paper reviews the work in the author's laboratory on the conversion of testosterone to 5 alpha-reduced metabolities and its regulatory control in intact pituitary, in enzymatically dispersed pituitary cells and in enriched populations of gonadotrophs isolated by unit gravity sedimentation. The data show that 5 alpha-reductase is located mainly in gonadotrophs and the possible physiological significance is discussed. A new culture method, suitable to study the regulation of 5 alpha-reductase and its biological significance in vitro, is presented.
ISSN: 0022-4731
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pharmacology Section (-)
× corresponding author
# (joint) last author

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