Title: Calcium ion homeostasis in smooth muscle
Authors: Missiaen, Ludwig ×
De Smedt, Humbert
Droogmans, Guillaume
Himpens, Bernard
Casteels, Rik #
Issue Date: May-1993
Series Title: Pharmacology & therapeutics. vol:56 issue:2 pages:191-231
Abstract: Ca2+ plays an important role in the regulation of smooth-muscle contraction. In this review, we will focus on the various Ca(2+)-transport processes that contribute to the cytosolic Ca2+ concentration. Mainly the functional aspects will be covered. The smooth-muscle inositol 1,4,5-trisphosphate receptor and ryanodine receptor will be extensively discussed. Smooth-muscle contraction also depends on extracellular Ca2+ and both voltage- and Ca(2+)-release-activated plasma-membrane Ca2+ channels will be reviewed. We will finally discuss some functional properties of the Ca2+ pumps that remove Ca2+ from the cytoplasm and of the Ca2+ regulation of the nucleus.
ISSN: 0163-7258
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Physiology Section (-)
Pharmacology Section (-)
Laboratory of Molecular and Cellular Signaling
× corresponding author
# (joint) last author

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