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Title: Antibodies against the non-muscle isoform of the endoplasmic reticulum Ca2(+)-transport ATPase
Authors: Wuytack, Frank ×
Eggermont, Jan
Raeymaekers, Luc
Plessers, L
Casteels, Rik #
Issue Date: Feb-1989
Series Title: The Biochemical journal. vol:264 issue:3 pages:765-9
Abstract: We report here the production of a polyclonal antiserum which specifically recognizes an epitope confined to the ultimate 12-residue-long C-terminus of an alternatively spliced transcript of gene 2 encoding the sarcoplasmic reticulum Ca2+ pump in slow skeletal and cardiac muscle. This alternatively spliced transcript was shown to be mainly represented in non-muscle tissues. These antibodies have enabled us to show the presence of the unique C-terminus of this type of Ca2+ pump, as predicted from the cDNA sequence, in the endoplasmic reticulum of vascular and gastric smooth muscle, liver and kidney.
ISSN: 0264-6021
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Physiology Section (-)
Laboratory of Cellular Transport Systems
× corresponding author
# (joint) last author

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