Author:

Keywords:

heart failure, myoblasts, myocardial infarction, stem cells, transplantation, doppler-echocardiographic evidence, left-ventricular dysfunction, myocardial-infarction, skeletal myoblasts, heart-failure, follow-up, injection, cells, model, revascularization, Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Peripheral Vascular Disease, Cardiovascular System & Cardiology, DOPPLER-ECHOCARDIOGRAPHIC EVIDENCE, MYOCARDIAL-INFARCTION, SKELETAL MYOBLASTS, HEART-FAILURE, FOLLOW-UP, INJECTION, CELLS, REVASCULARIZATION, IMPLANTATION, RECOVERY, Aged, Cardiomyopathies, Double-Blind Method, Female, Follow-Up Studies, Humans, Male, Middle Aged, Myoblasts, Skeletal, Myocardial Ischemia, Transplantation, Autologous, Transplants, 1102 Cardiorespiratory Medicine and Haematology, 1103 Clinical Sciences, 1117 Public Health and Health Services, Cardiovascular System & Hematology, 3201 Cardiovascular medicine and haematology, 3202 Clinical sciences, 4207 Sports science and exercise

Abstract:

Background-Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they have failed to determine whether this procedure was functionally effective and arrhythmogenic.