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Eurosurveillance

Publication date: 2024-09-19
Volume: 29
Publisher: European Centre for Disease Prevention and Control

Author:

Wawina-Bokalanga, Tony
Akil-Bandali, Prince ; Kinganda-Lusamaki, Eddy ; Lokilo, Emmanuel ; Jansen, Daan ; Amuri-Aziza, Adrienne ; Makangara-Cigolo, Jean-Claude ; Pukuta-Simbu, Elisabeth ; Ola-Mpumbe, Rilia ; Muyembe, Mamito ; Kacita, Cris ; Paku-Tshambu, Princesse ; Dantas, Pedro HLF ; Tshiani-Mbaya, Olivier ; Luakanda, Gradi ; Nkuba-Ndaye, Antoine ; Matondo, Meris ; Vakaniaki, Emmanuel Hasivirwe ; Tessema, Sofonias ; Ndembi, Nicaise ; O'Toolesss, Aine ; De Block, Tessa ; Ngandu, Christian ; Hoff, Nicole A ; Low, Nicola ; Subissi, Lorenzo ; Merritt, Sydney ; Muyembe-Tamfum, Jean-Jacques ; Liesenborghs, Laurens ; Peeters, Martine ; Delaporte, Eric ; Kindrachuk, Jason ; Rimoin, Anne ; Ahuka-Mundeke, Steve ; Rambau, Andrew ; Mwamba, Dieudonne ; Vercauteren, Koen ; Mbala-Kingebeni, Placide

Keywords:

Science & Technology, Life Sciences & Biomedicine, Infectious Diseases, Clade I, Co-circulation, Democratic Republic of the Congo, Kinshasa, Monkeypox virus (MPXV), Mpox, public health policy, surveillance, Mpox, Monkeypox, Humans, Monkeypox virus, Phylogeny, Disease Outbreaks, Genome, Viral, RNA, Viral, Male, Sequence Analysis, DNA, Mpox (monkeypox), 0605 Microbiology, 1117 Public Health and Health Services, 1199 Other Medical and Health Sciences, 4202 Epidemiology

Abstract:

Between January and August 2024, mpox cases have been reported in nearly all provinces of the Democratic Republic of the Congo (DRC). Monkeypox virus genome sequences were obtained from 11 mpox cases' samples, collected in July-August 2024 in several health zones of Kinshasa. Characterisation of the sequences showed subclades Ia and Ib co-circulating in the Limete health zone, while phylogenetic analyses suggested multiple introductions of the two subclades in Kinshasa. This illustrates the growing complexity of Clade I mpox outbreaks in DRC.