Download PDF (external access)

Journal of Clinical Endocrinology & Metabolism

Publication date: 2012-03
Volume: 97 Pages: 978 - 986
ISSN: 0021-972X, 1945-7197 PMID: 22259067
DOI: 10.1210/jc.2011-1096
Publisher: Issued for the Endocrine Society by the Williams & Wilkins Co.


Knuever, Jana
Poeggeler, Burkhard ; Gáspár, Erzsébet ; Klinger, Matthias ; Hellwig-Burgel, Thomas ; Hardenbicker, Celine ; Tóth, Balázs István ; Bíró, Tamás ; Paus, Ralf


Adult, Energy Metabolism, Epidermis, Humans, Middle Aged, Mitochondria, Organ Culture Techniques, Receptors, Thyrotropin-Releasing Hormone, Thyrotropin-Releasing Hormone, 1103 Clinical Sciences, 1114 Paediatrics and Reproductive Medicine, Endocrinology & Metabolism


Mitochondrial capacity and metabolic potential are under the control of hormones, such as thyroid hormones. The most proximal regulator of the hypothalamic-pituitary-thyroid (HPT) axis, TRH, is the key hypothalamic integrator of energy metabolism via its impact on thyroid hormone secretion.