The aim of this work is to study the energetic properties of commercially pure titanium samples due to different surface treatments and different sterilization methods; with the purpose to understand how these changes affect to the biological processes of titanium implants. The different surface treatments were: roughness obtained by shot blasting, and sterilization by steam autoclaving, ethylene oxide or gamma radiation. Roughness level and the nature of the abrasive particles of shot blasting influence energetically the samples; increasing the hydrophobic behaviour with the increase of the surface roughness and the alumina use. The contamination due to steam autoclaving hydrophobizes the surface; contrary to sterilization by ethylene oxide, which reduces the contact angle value. The modification of treated surfaces was examined with a series of surface analytical techniques that include the scanning electron microscopy (SEM), the white light interferometer microscopy and the static contact angle measurement in order to determine a qualitative and quantitative topographic characterization and an energetic characterization.