American Journal of Medical Genetics

Publication date: 1995-09
Volume: 58 Pages: 360 -
ISSN: 0148-7299, 1096-8628 PMID: 8533847
DOI: 10.1002/ajmg.1320580412
Publisher: Wiley-Liss


Dietzsch, E
Ramsay, M ; Christianson, AL ; Henderson, BD ; de Ravel de l'Argentière, Thomy


Adult, Chromosome Aberrations, Chromosome Disorders, Female, Fetal Growth Retardation, Genetic Markers, Genomic Imprinting, Gestational Age, Humans, Infant, Newborn, Male, Meiosis, Oogenesis, Polyploidy, Pregnancy, 1103 Clinical Sciences, 0604 Genetics


Twenty-six highly polymorphic markers were used to determine the origin of the extra haploid chromosome set in 6 triploid fetuses of type II phenotype. All had reached the third trimester of pregnancy. The extra set was maternal in origin in all cases, supporting previous research indicating longer in utero survival of maternally-derived triploid fetuses. These findings provide evidence for an instance of genomic imprinting in humans.