Nanomedicine

Publication date: 2013-01
Pages: 77 - 87
ISSN: 1743-5889, 1748-6963 PMID: 22891862
DOI: 10.2217/nnm.12.97
Publisher: Future Medicine Ltd.

Author:

De Haes, Winni
Rejman, Joanna ; Pollard, Charlotte ; Merlin, Céline ; Vekemans, Marc ; Florence, Eric ; De Smedt, Stefaan C ; Grooten, Johan ; Vanham, Guido ; De Koker, Stefaan ; Van Gulck, Ellen

Keywords:

Dendritic Cells, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Gene Products, gag, HIV, Humans, Immunophenotyping, Microscopy, Fluorescence, RNA, Messenger, 1004 Medical Biotechnology, 1007 Nanotechnology, 0306 Physical Chemistry (incl. Structural), Nanoscience & Nanotechnology

Abstract:

Cationic lipids (Lipofectamine™ [Invitrogen, Merelbeke, Belgium] and 1,2-dioleoyl-3-trimethylammonium-propane/1,2-dioleoyl-sn-glycero-3-phosphoethanolamine) and polymers (jetPEI™ and in vivo-jetPEI™ [Polyplus-transfection, Illkirch, France]) were evaluated for their potential to deliver mRNA to monocyte-derived dendritic cells.