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Human Brain Mapping

Publication date: 2009-12
Volume: 30 Pages: 3970 - 80
ISSN: 1065-9471, 1097-0193 PMID: 19449333
DOI: 10.1002/hbm.20822
Publisher: Wiley-Liss

Author:

Raemaekers, Mathijs
Lankheet, Martin JM ; Moorman, Sanne ; Kourtzi, Zoe ; van Wezel, Richard JA

Keywords:

Anisotropy, Brain Mapping, Humans, Magnetic Resonance Imaging, Motion Perception, Visual Cortex, Science & Technology, Life Sciences & Biomedicine, Neurosciences, Neuroimaging, Radiology, Nuclear Medicine & Medical Imaging, Neurosciences & Neurology, fMRI, motion, vision, visual motion, MT, occipital, HUMAN VISUAL-CORTEX, HUMAN BRAIN, FUNCTIONAL ARCHITECTURE, SPATIAL ATTENTION, AREA MT, FIELD, SENSITIVITY, NEURONS, MACAQUE, BIAS, Experimental Psychology, 1109 Neurosciences, 1702 Cognitive Sciences

Abstract:

Recently, evidence has emerged for a radial orientation bias in early visual cortex. These results predict that in early visual cortex a tangential bias should be present for motion direction. We tested this prediction in a human imaging study, using a translating random dot pattern that slowly rotated its motion direction 360 degrees in cycles of 54 s. In addition, polar angle and eccentricity mapping were performed. This allowed the measurement of the BOLD response across the visual representations of the different retinotopic areas. We found that, in V1, V2, and V3, BOLD responses were consistently enhanced for centrifugal and centripetal motion, relative to tangential motion. The relative magnitude of the centrifugal and centripetal response biases changed with visual eccentricity. We found no motion direction biases in MT+. These results are in line with previously observed anisotropies in motion sensitivity across the visual field. However, the observation of radial motion biases in early visual cortex is surprising considering the evidence for a radial orientation bias. An additional experiment was performed to resolve this apparent conflict in results. The additional experiment revealed that the observed motion direction biases most likely originate from anisotropies in long range horizontal connections within visual cortex.