Author:

Keywords:

Science & Technology, Life Sciences & Biomedicine, Allergy, Dermatology, allergic contact dermatitis, copolymer, cosmetics, methoxy PEG-17/dodecyl glycol, methoxy PEG-22/dodecyl glycol, phthalic anhydride/trimellitic anhydride/glycols copolymer, polyvinyl methyl/maleic acid copolymer, PVP/1-triacontene, PVP/eicosene, PVP/hexadecene, sunscreens, ANHYDRIDE/TRIMELLITIC ANHYDRIDE/GLYCOLS COPOLYMER, Adult, Allergens, Cosmetics, Dermatitis, Allergic Contact, Humans, Male, Maleic Anhydrides, Pharmaceutic Aids, Phthalic Anhydrides, Polyethylene Glycols, Polymers, Polyvinyls, Povidone, Surface-Active Agents, 1103 Clinical Sciences, 1107 Immunology, Dermatology & Venereal Diseases, 3202 Clinical sciences, 3204 Immunology

Abstract:

Copolymers or heteropolymers are large molecules with high molecular weights (>1000 D). They have been underestimated for a long time as to their sensitizing capacities. Allergic contact dermatitis to 6 copolymers in cosmetics and 1 in a medical dressing has been described; however, the nature of the hapten is still unknown. We report a case of allergic contact dermatitis to polyvinylpyrrolidone (PVP)/hexadecene copolymer in a purple-colored lipstick and review the literature on allergic contact dermatitis to 7 copolymers: PVP/hexadecene, PVP/eicosene, PVP/1-triacontene, methoxy polyethyleneglycol (PEG)-22/dodecyl glycols, methoxy PEG-17/dodecyl glycols, phthalic anhydride/trimellitic anhydride/glycols, and polyvinyl methyl/maleic acid anhydride.